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IMRAS—Immunization with radiation-attenuated Plasmodium falciparum sporozoites by mosquito bite: Cellular immunity to sporozoites, CSP, AMA1, TRAP and CelTOS
BACKGROUND: Immunization with radiation-attenuated sporozoites (RAS) by mosquito bites provides >90% sterile protection against Plasmodium falciparum malaria in humans. We conducted a clinical trial based on data from previous RAS clinical trials that suggested that 800–1200 infected bites should...
Autores principales: | Sedegah, Martha, Hollingdale, Michael R., Ganeshan, Harini, Belmonte, Maria, Huang, Jun, Belmonte, Arnel, Inoue, Sandra, Velasco, Rachel, Hickey, Bradley, Teneza-Mora, Nimfa, Lumsden, Joanne, Reyes, Sharina, Banania, Jo Glenna, Reyes, Anatalio, Guzman, Ivelese, Richie, Thomas L., Epstein, Judith E., Villasante, Eileen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378721/ https://www.ncbi.nlm.nih.gov/pubmed/34415964 http://dx.doi.org/10.1371/journal.pone.0256396 |
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