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Core circadian clock transcription factor BMAL1 regulates mammary epithelial cell growth, differentiation, and milk component synthesis

The role the mammary epithelial circadian clock plays in gland development and lactation is unknown. We hypothesized that mammary epithelial clocks function to regulate mammogenesis and lactogenesis, and propose the core clock transcription factor BMAL1:CLOCK regulates genes that control mammary epi...

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Detalles Bibliográficos
Autores principales: Casey, Theresa, Suarez-Trujillo, Aridany, Cummings, Shelby, Huff, Katelyn, Crodian, Jennifer, Bhide, Ketaki, Aduwari, Clare, Teeple, Kelsey, Shamay, Avi, Mabjeesh, Sameer J., San Miguel, Phillip, Thimmapuram, Jyothi, Plaut, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378744/
https://www.ncbi.nlm.nih.gov/pubmed/34415905
http://dx.doi.org/10.1371/journal.pone.0248199