Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing

DNA methylation is an epigenetic process that controls DNA accessibility and serves as a transcriptomic switch when deposited at regulatory regions. The adequate functioning of this process is indispensable for tissue homeostasis and cell fate determination. Conversely, altered DNA methylation patte...

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Detalles Bibliográficos
Autores principales: Vizoso, Miguel, van Rheenen, Jacco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378768/
https://www.ncbi.nlm.nih.gov/pubmed/34434494
http://dx.doi.org/10.18632/oncotarget.28037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378768/
https://www.ncbi.nlm.nih.gov/pubmed/34434494
http://dx.doi.org/10.18632/oncotarget.28037

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