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A Vaccine Based on the Receptor-Binding Domain of the Spike Protein Expressed in Glycoengineered Pichia pastoris Targeting SARS-CoV-2 Stimulates Neutralizing and Protective Antibody Responses

In 2020 and 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, caused a global pandemic. Vaccines are expected to reduce the pressure of prevention and control, and have become the most effective strategy to solve the pandemic crisis. SARS-CoV-2 infects the host...

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Detalles Bibliográficos
Autores principales: Liu, Bo, Yin, Ying, Liu, Yuxiao, Wang, Tiantian, Sun, Peng, Ou, Yangqin, Gong, Xin, Hou, Xuchen, Zhang, Jun, Ren, Hongguang, Luo, Shiqiang, Ke, Qian, Yao, Yongming, Xu, Junjie, Wu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: THE AUTHORS. Published by Elsevier LTD on behalf of Chinese Academy of Engineering and Higher Education Press Limited Company. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378774/
https://www.ncbi.nlm.nih.gov/pubmed/34457370
http://dx.doi.org/10.1016/j.eng.2021.06.012