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What can reaction databases teach us about Buchwald–Hartwig cross-couplings?

Despite the widespread and increasing usage of Pd-catalyzed C–N cross couplings, finding good conditions for these reactions can be challenging. Practitioners mostly rely on few methodology studies or anecdotal experience. This is surprising, since the advent of data-driven experimentation and the l...

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Detalles Bibliográficos
Autores principales: Fitzner, Martin, Wuitschik, Georg, Koller, Raffael J., Adam, Jean-Michel, Schindler, Torsten, Reymond, Jean-Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378852/
https://www.ncbi.nlm.nih.gov/pubmed/34476050
http://dx.doi.org/10.1039/d0sc04074f