TDO2 Was Downregulated in Hepatocellular Carcinoma and Inhibited Cell Proliferation by Upregulating the Expression of p21 and p27

BACKGROUND: Tryptophan-2,3-dioxygenase (TDO2) converts tryptophan into kynurenine in the initial limiting step of the kynurenine pathway. During the past decade, the overexpression of TDO2 has been found in various human tumors. However, the role of TDO2 in hepatocellular carcinoma is controversial,...

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Detalles Bibliográficos
Autores principales: Yu, Chengpeng, Rao, Dean, Zhu, He, Liu, Qiumeng, Huang, Wenjie, Zhang, Long, Liang, Huifang, Song, Jia, Ding, Zeyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378971/
https://www.ncbi.nlm.nih.gov/pubmed/34423034
http://dx.doi.org/10.1155/2021/4708439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378971/
https://www.ncbi.nlm.nih.gov/pubmed/34423034
http://dx.doi.org/10.1155/2021/4708439

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