Computer-aided prediction of inhibitors against STAT3 for managing COVID-19 associated cytokine storm

BACKGROUND: Proinflammatory cytokines are correlated with the severity of disease in patients with COVID-19. IL6-mediated activation of STAT3 proliferates proinflammatory responses that lead to cytokine storm promotion. Thus, STAT3 inhibitors may play a crucial role in managing the COVID-19 pathogen...

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Detalles Bibliográficos
Autores principales: Dhall, Anjali, Patiyal, Sumeet, Sharma, Neelam, Devi, Naorem Leimarembi, Raghava, Gajendra.P.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378993/
https://www.ncbi.nlm.nih.gov/pubmed/34450382
http://dx.doi.org/10.1016/j.compbiomed.2021.104780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378993/
https://www.ncbi.nlm.nih.gov/pubmed/34450382
http://dx.doi.org/10.1016/j.compbiomed.2021.104780

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