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Activation of FcRn Mediates a Primary Resistance Response to Sorafenib in Hepatocellular Carcinoma by Single-Cell RNA Sequencing

Sorafenib is the first-line therapeutic option for advanced hepatocellular carcinoma (HCC). Many patients exhibit a primary resistance (PR) response after initial treatment. In previous studies, compared to acquired resistance, the mechanism of PR is unclear. The present study aimed to evaluate the...

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Detalles Bibliográficos
Autores principales: Guan, Xin, Wu, Yi, Zhang, Shuqin, Liu, Zhiyi, Fan, Qingjie, Fang, Shuai, Qiao, Sennan, Sun, Fei, Liang, Chongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379008/
https://www.ncbi.nlm.nih.gov/pubmed/34421602
http://dx.doi.org/10.3389/fphar.2021.709343