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Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection

The majority of HIV infections are established through the genital or rectal mucosa. Fibroblasts are abundant in these tissues, and although not susceptible to infection, can potently enhance HIV infection of CD4+ T cells. Hyaluronic acid (HA) is a major component of the extracellular matrix of fibr...

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Detalles Bibliográficos
Autores principales: Egedal, Johanne H., Xie, Guorui, Packard, Thomas A., Laustsen, Anders, Neidleman, Jason, Georgiou, Konstantinos, Pillai, Satish K., Greene, Warner C., Jakobsen, Martin R., Roan, Nadia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379073/
https://www.ncbi.nlm.nih.gov/pubmed/33976386
http://dx.doi.org/10.1038/s41385-021-00409-3