IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F(+) neutrophils

Understanding the mechanism of protective immunity in the nasal mucosae is central to the design of more effective vaccines that prevent nasal infection and transmission of Bordetella pertussis. We found significant infiltration of IL-17-secreting CD4(+) tissue-resident memory T (T(RM)) cells and Si...

Descripción completa

Detalles Bibliográficos
Autores principales: Borkner, Lisa, Curham, Lucy M., Wilk, Mieszko M., Moran, Barry, Mills, Kingston H. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379078/
https://www.ncbi.nlm.nih.gov/pubmed/33976385
http://dx.doi.org/10.1038/s41385-021-00407-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379078/
https://www.ncbi.nlm.nih.gov/pubmed/33976385
http://dx.doi.org/10.1038/s41385-021-00407-5

Ejemplares similares