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Tetra-gel enables superior accuracy in combined super-resolution imaging and expansion microscopy

The accuracy of expansion microscopy (ExM) depends on the structural preservation of samples embedded in a hydrogel. However, it has been unknown to what extent gel embedding alters the molecular positions of individual labeled sites. Here, we quantified the accuracy of gel embedding by using stocha...

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Detalles Bibliográficos
Autores principales: Lee, Hsuan, Yu, Chih-Chieh, Boyden, Edward S., Zhuang, Xiaowei, Kosuri, Pallav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379153/
https://www.ncbi.nlm.nih.gov/pubmed/34417516
http://dx.doi.org/10.1038/s41598-021-96258-y