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UbiD domain dynamics underpins aromatic decarboxylation
The widespread UbiD enzyme family utilises the prFMN cofactor to achieve reversible decarboxylation of acrylic and (hetero)aromatic compounds. The reaction with acrylic compounds based on reversible 1,3-dipolar cycloaddition between substrate and prFMN occurs within the confines of the active site....
Autores principales: | Marshall, Stephen A., Payne, Karl A. P., Fisher, Karl, Titchiner, Gabriel R., Levy, Colin, Hay, Sam, Leys, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379154/ https://www.ncbi.nlm.nih.gov/pubmed/34417452 http://dx.doi.org/10.1038/s41467-021-25278-z |
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