The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter

Depression is a common mental disorder. The standard medical treatment is the selective serotonin reuptake inhibitors (SSRIs). All characterized SSRIs are competitive inhibitors of the serotonin transporter (SERT). A non-competitive inhibitor may produce a more favorable therapeutic profile. Vilazod...

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Detalles Bibliográficos
Autores principales: Plenge, Per, Yang, Dongxue, Salomon, Kristine, Laursen, Louise, Kalenderoglou, Iris E., Newman, Amy H., Gouaux, Eric, Coleman, Jonathan A., Loland, Claus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379219/
https://www.ncbi.nlm.nih.gov/pubmed/34417466
http://dx.doi.org/10.1038/s41467-021-25363-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379219/
https://www.ncbi.nlm.nih.gov/pubmed/34417466
http://dx.doi.org/10.1038/s41467-021-25363-3

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