Uridine treatment prevents myocardial injury in rat models of acute ischemia and ischemia/reperfusion by activating the mitochondrial ATP-dependent potassium channel

The effect of uridine on the myocardial ischemic and reperfusion injury was investigated. A possible mechanism of its cardioprotective action was established. Two rat models were used: (1) acute myocardial ischemia induced by occlusion of the left coronary artery for 60 min; and (2) myocardial ische...

Descripción completa

Detalles Bibliográficos
Autores principales: Krylova, Irina B., Selina, Elena N., Bulion, Valentina V., Rodionova, Olga M., Evdokimova, Natalia R., Belosludtseva, Natalia V., Shigaeva, Maria I., Mironova, Galina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379228/
https://www.ncbi.nlm.nih.gov/pubmed/34417540
http://dx.doi.org/10.1038/s41598-021-96562-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379228/
https://www.ncbi.nlm.nih.gov/pubmed/34417540
http://dx.doi.org/10.1038/s41598-021-96562-7

Ejemplares similares