Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction

T-cell activation and cellular expansion by common gamma chain cytokines such as Interleukin-2 is necessary for adaptive immunity. However, when unregulated these same pathways promote pathologies ranging from autoimmune disorders to cancer. While the functional role of Interleukin-2 and downstream...

Descripción completa

Detalles Bibliográficos
Autores principales: Estrada, Armando, Rodriguez, Alejandro C., Rodriguez, Georgialina, Grant, Alice H., Ayala-Marin, Yoshira M., Arrieta, Amy J., Kirken, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379229/
https://www.ncbi.nlm.nih.gov/pubmed/34417497
http://dx.doi.org/10.1038/s41598-021-96428-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379229/
https://www.ncbi.nlm.nih.gov/pubmed/34417497
http://dx.doi.org/10.1038/s41598-021-96428-y

Ejemplares similares