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Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction

T-cell activation and cellular expansion by common gamma chain cytokines such as Interleukin-2 is necessary for adaptive immunity. However, when unregulated these same pathways promote pathologies ranging from autoimmune disorders to cancer. While the functional role of Interleukin-2 and downstream...

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Detalles Bibliográficos
Autores principales:	Estrada, Armando, Rodriguez, Alejandro C., Rodriguez, Georgialina, Grant, Alice H., Ayala-Marin, Yoshira M., Arrieta, Amy J., Kirken, Robert A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379229/ https://www.ncbi.nlm.nih.gov/pubmed/34417497 http://dx.doi.org/10.1038/s41598-021-96428-y

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