MethylSPWNet and MethylCapsNet: Biologically Motivated Organization of DNAm Neural Networks, Inspired by Capsule Networks

DNA methylation (DNAm) alterations have been heavily implicated in carcinogenesis and the pathophysiology of diseases through upstream regulation of gene expression. DNAm deep-learning approaches are able to capture features associated with aging, cell type, and disease progression, but lack incorpo...

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Detalles Bibliográficos
Autores principales: Levy, Joshua J., Chen, Youdinghuan, Azizgolshani, Nasim, Petersen, Curtis L., Titus, Alexander J., Moen, Erika L., Vaickus, Louis J., Salas, Lucas A., Christensen, Brock C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Technology Feature
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379254/
https://www.ncbi.nlm.nih.gov/pubmed/34417465
http://dx.doi.org/10.1038/s41540-021-00193-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379254/
https://www.ncbi.nlm.nih.gov/pubmed/34417465
http://dx.doi.org/10.1038/s41540-021-00193-7

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