A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice

Reduced glucose uptake into the skeletal muscle is an important pathophysiological abnormality in type 2 diabetes, and is caused by impaired translocation of glucose transporter 4 (GLUT4) to the skeletal muscle cell surface. Here, we show a xanthene derivative, DS20060511, induces GLUT4 translocatio...

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Detalles Bibliográficos
Autores principales: Furuzono, Shinji, Kubota, Tetsuya, Taura, Junki, Konishi, Masahiro, Naito, Asuka, Tsutsui, Masato, Karasawa, Hiroshi, Kubota, Naoto, Kadowaki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379256/
https://www.ncbi.nlm.nih.gov/pubmed/34417555
http://dx.doi.org/10.1038/s42003-021-02491-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379256/
https://www.ncbi.nlm.nih.gov/pubmed/34417555
http://dx.doi.org/10.1038/s42003-021-02491-6

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