Cargando…
A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice
Reduced glucose uptake into the skeletal muscle is an important pathophysiological abnormality in type 2 diabetes, and is caused by impaired translocation of glucose transporter 4 (GLUT4) to the skeletal muscle cell surface. Here, we show a xanthene derivative, DS20060511, induces GLUT4 translocatio...
Autores principales: | Furuzono, Shinji, Kubota, Tetsuya, Taura, Junki, Konishi, Masahiro, Naito, Asuka, Tsutsui, Masato, Karasawa, Hiroshi, Kubota, Naoto, Kadowaki, Takashi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379256/ https://www.ncbi.nlm.nih.gov/pubmed/34417555 http://dx.doi.org/10.1038/s42003-021-02491-6 |
Ejemplares similares
-
Glut1 Deficiency Syndrome (Glut1DS): State of the art in 2020 and recommendations of the international Glut1DS study group
por: Klepper, Joerg, et al.
Publicado: (2020) -
Clinical Variability of GLUT1DS
por: Melnikova, Anastasia Martinez-Esteve, et al.
Publicado: (2015) -
Characterization of Speech and Language Phenotype in GLUT1DS
por: Zanaboni, Martina Paola, et al.
Publicado: (2021) -
BAG6 contributes to glucose uptake by supporting the cell surface translocation of the glucose transporter GLUT4
por: Minami, Setsuya, et al.
Publicado: (2020) -
Undaria pinnatifida (Wakame) Intake Ameliorates High-Fat Diet-Induced Glucose Intolerance via Promoting GLUT4 Expression and Membrane Translocation in Muscle
por: Imai, Motoki, et al.
Publicado: (2023)