Tet2 Controls the Responses of β cells to Inflammation in Autoimmune Diabetes

β cells may participate and contribute to their own demise during Type 1 diabetes (T1D). Here we report a role of their expression of Tet2 in regulating immune killing. Tet2 is induced in murine and human β cells with inflammation but its expression is reduced in surviving β cells. Tet2-KO mice that...

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Detalles Bibliográficos
Autores principales: Rui, Jinxiu, Deng, Songyan, Perdigoto, Ana Luisa, Ponath, Gerald, Kursawe, Romy, Lawlor, Nathan, Sumida, Tomokazu, Levine-Ritterman, Maya, Stitzel, Michael L., Pitt, David, Lu, Jun, Herold, Kevan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379260/
https://www.ncbi.nlm.nih.gov/pubmed/34417463
http://dx.doi.org/10.1038/s41467-021-25367-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379260/
https://www.ncbi.nlm.nih.gov/pubmed/34417463
http://dx.doi.org/10.1038/s41467-021-25367-z

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