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Dynamic landscape of chromatin accessibility and transcriptomic changes during differentiation of human embryonic stem cells into dopaminergic neurons

Chromatin architecture influences transcription by modulating the physical access of regulatory factors to DNA, playing fundamental roles in cell identity. Studies on dopaminergic differentiation have identified coding genes, but the relationship with non-coding genes or chromatin accessibility rema...

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Detalles Bibliográficos
Autores principales: Meléndez-Ramírez, César, Cuevas-Diaz Duran, Raquel, Barrios-García, Tonatiuh, Giacoman-Lozano, Mayela, López-Ornelas, Adolfo, Herrera-Gamboa, Jessica, Estudillo, Enrique, Soto-Reyes, Ernesto, Velasco, Iván, Treviño, Víctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379280/
https://www.ncbi.nlm.nih.gov/pubmed/34417498
http://dx.doi.org/10.1038/s41598-021-96263-1