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Matrix stiffness modulates tip cell formation through the p-PXN-Rac1-YAP signaling axis
Endothelial tip cell outgrowth of blood-vessel sprouts marks the initiation of angiogenesis which is critical in physiological and pathophysiological procedures. However, how mechanical characteristics of extracellular matrix (ECM) modulates tip cell formation has been largely neglected. In this stu...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379356/ https://www.ncbi.nlm.nih.gov/pubmed/34466738 http://dx.doi.org/10.1016/j.bioactmat.2021.05.033 |