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Matrix stiffness modulates tip cell formation through the p-PXN-Rac1-YAP signaling axis

Endothelial tip cell outgrowth of blood-vessel sprouts marks the initiation of angiogenesis which is critical in physiological and pathophysiological procedures. However, how mechanical characteristics of extracellular matrix (ECM) modulates tip cell formation has been largely neglected. In this stu...

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Detalles Bibliográficos
Autores principales: Guo, Yaru, Mei, Feng, Huang, Ying, Ma, Siqin, Wei, Yan, Zhang, Xuehui, Xu, Mingming, He, Ying, Heng, Boon Chin, Chen, Lili, Deng, Xuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379356/
https://www.ncbi.nlm.nih.gov/pubmed/34466738
http://dx.doi.org/10.1016/j.bioactmat.2021.05.033