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Targeted and intracellular delivery of protein therapeutics by a boronated polymer for the treatment of bone tumors

The treatment of malignant bone tumors by chemotherapeutics often receives poor therapeutic response due to the specific physiological bone environment, and thus calls for the development of new therapeutic options. Here, we reported a bone-targeted protein nanomedicine for this purpose. Saporin, a...

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Detalles Bibliográficos
Autores principales: Yan, Yang, Zhou, Lei, Sun, Zhengwang, Song, Dianwen, Cheng, Yiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379369/
https://www.ncbi.nlm.nih.gov/pubmed/34466736
http://dx.doi.org/10.1016/j.bioactmat.2021.05.041