Tumor acid microenvironment-activated self-targeting & splitting gold nanoassembly for tumor chemo-radiotherapy

Low accumulation and penetration of nanomedicines in tumor severely reduce therapeutic efficacy. Herein, a pH-responsive gold nanoassembly is designed to overcome these problems. Polyethylene glycol linked raltitrexed (RTX, target ligand and chemotherapy drug) and two tertiary amine molecules (1-(2-...

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Detalles Bibliográficos
Autores principales: Li, Xiaomin, Yu, Licheng, Zhang, Chuangnian, Niu, Xiaoyan, Sun, Mengjie, Yan, Zichao, Wang, Wei, Yuan, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379383/
https://www.ncbi.nlm.nih.gov/pubmed/34466739
http://dx.doi.org/10.1016/j.bioactmat.2021.05.050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379383/
https://www.ncbi.nlm.nih.gov/pubmed/34466739
http://dx.doi.org/10.1016/j.bioactmat.2021.05.050

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