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Skeletal FGFR1 signaling is necessary for regulation of serum phosphate level by FGF23 and normal life span

Fibroblast growth factor (FGF) 23 produced by the bone is the principal hormone to regulate serum phosphate level. Serum FGF23 needs to be tightly regulated to maintain serum phosphate in a narrow range. Thus, we hypothesized that the bone has some phosphate-sensing mechanism to regulate the product...

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Detalles Bibliográficos
Autores principales: Takashi, Yuichi, Sawatsubashi, Shun, Endo, Itsuro, Ohnishi, Yukiyo, Abe, Masahiro, Matsuhisa, Munehide, Kawanami, Daiji, Matsumoto, Toshio, Fukumoto, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379418/
https://www.ncbi.nlm.nih.gov/pubmed/34458594
http://dx.doi.org/10.1016/j.bbrep.2021.101107