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High-throughput drug screening models of mature adipose tissues which replicate the physiology of patients’ Body Mass Index (BMI)

Obesity is a complex and incompletely understood disease, but current drug screening strategies mostly rely on immature in vitro adipose models which cannot recapitulate it properly. To address this issue, we developed a statistically validated high-throughput screening model by seeding human mature...

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Detalles Bibliográficos
Autores principales: Louis, Fiona, Sowa, Yoshihiro, Kitano, Shiro, Matsusaki, Michiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379425/
https://www.ncbi.nlm.nih.gov/pubmed/34466729
http://dx.doi.org/10.1016/j.bioactmat.2021.05.020