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High-throughput drug screening models of mature adipose tissues which replicate the physiology of patients’ Body Mass Index (BMI)
Obesity is a complex and incompletely understood disease, but current drug screening strategies mostly rely on immature in vitro adipose models which cannot recapitulate it properly. To address this issue, we developed a statistically validated high-throughput screening model by seeding human mature...
Autores principales: | Louis, Fiona, Sowa, Yoshihiro, Kitano, Shiro, Matsusaki, Michiya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379425/ https://www.ncbi.nlm.nih.gov/pubmed/34466729 http://dx.doi.org/10.1016/j.bioactmat.2021.05.020 |
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