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Phospholipid exchange shows insulin receptor activity is supported by both the propensity to form wide bilayers and ordered raft domains

Insulin receptor (IR) is a membrane tyrosine kinase that mediates the response of cells to insulin. IR activity has been shown to be modulated by changes in plasma membrane lipid composition, but the properties and structural determinants of lipids mediating IR activity are poorly understood. Here,...

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Detalles Bibliográficos
Autores principales: Suresh, Pavana, Miller, W. Todd, London, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379460/
https://www.ncbi.nlm.nih.gov/pubmed/34324831
http://dx.doi.org/10.1016/j.jbc.2021.101010