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Phospholipid exchange shows insulin receptor activity is supported by both the propensity to form wide bilayers and ordered raft domains
Insulin receptor (IR) is a membrane tyrosine kinase that mediates the response of cells to insulin. IR activity has been shown to be modulated by changes in plasma membrane lipid composition, but the properties and structural determinants of lipids mediating IR activity are poorly understood. Here,...
Autores principales: | Suresh, Pavana, Miller, W. Todd, London, Erwin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379460/ https://www.ncbi.nlm.nih.gov/pubmed/34324831 http://dx.doi.org/10.1016/j.jbc.2021.101010 |
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