Cargando…
Effects of excitotoxicity in the hypothalamus in transgenic mouse models of Huntington disease
Huntington disease (HD) is a fatal neurodegenerative movement disorder caused by an expanded CAG repeat in the huntingtin gene (HTT). The mutant huntingtin protein is ubiquitously expressed, but only certain brain regions are affected. The hypothalamus has emerged as an important area of pathology w...
Autores principales: | Henningsen, Jo B., Soylu-Kucharz, Rana, Björkqvist, Maria, Petersén, Åsa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379469/ https://www.ncbi.nlm.nih.gov/pubmed/34458633 http://dx.doi.org/10.1016/j.heliyon.2021.e07808 |
Ejemplares similares
-
IKKβ signaling mediates metabolic changes in the hypothalamus of a Huntington disease mouse model
por: Soylu-Kucharz, Rana, et al.
Publicado: (2022) -
Hypothalamic expression of huntingtin causes distinct metabolic changes in Huntington's disease mice
por: Dickson, Elna, et al.
Publicado: (2022) -
Microarray profiling of hypothalamic gene expression changes in Huntington’s disease mouse models
por: Dickson, Elna, et al.
Publicado: (2022) -
Metabolic and behavioral effects of mutant huntingtin deletion in Sim1 neurons in the BACHD mouse model of Huntington’s disease
por: Soylu-Kucharz, Rana, et al.
Publicado: (2016) -
Neurofilament light protein in CSF and blood is associated with neurodegeneration and disease severity in Huntington’s disease R6/2 mice
por: Soylu-Kucharz, Rana, et al.
Publicado: (2017)