Cargando…

Ablation of glucokinase-expressing tanycytes impacts energy balance and increases adiposity in mice

OBJECTIVES: Glucokinase (GCK) is critical for glucosensing. In rats, GCK is expressed in hypothalamic tanycytes and appears to play an essential role in feeding behavior. In this study, we investigated the distribution of GCK-expressing tanycytes in mice and their role in the regulation of energy ba...

Descripción completa

Detalles Bibliográficos
Autores principales: Rohrbach, Antoine, Caron, Emilie, Dali, Rafik, Brunner, Maxime, Pasquettaz, Roxane, Kolotuev, Irina, Santoni, Federico, Thorens, Bernard, Langlet, Fanny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379510/
https://www.ncbi.nlm.nih.gov/pubmed/34325016
http://dx.doi.org/10.1016/j.molmet.2021.101311