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Ablation of glucokinase-expressing tanycytes impacts energy balance and increases adiposity in mice
OBJECTIVES: Glucokinase (GCK) is critical for glucosensing. In rats, GCK is expressed in hypothalamic tanycytes and appears to play an essential role in feeding behavior. In this study, we investigated the distribution of GCK-expressing tanycytes in mice and their role in the regulation of energy ba...
Autores principales: | Rohrbach, Antoine, Caron, Emilie, Dali, Rafik, Brunner, Maxime, Pasquettaz, Roxane, Kolotuev, Irina, Santoni, Federico, Thorens, Bernard, Langlet, Fanny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379510/ https://www.ncbi.nlm.nih.gov/pubmed/34325016 http://dx.doi.org/10.1016/j.molmet.2021.101311 |
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