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Insulin-like growth factor II prevents oxidative and neuronal damage in cellular and mice models of Parkinson's disease

Oxidative distress and mitochondrial dysfunction, are key factors involved in the pathophysiology of Parkinson's disease (PD). The pleiotropic hormone insulin-like growth factor II (IGF-II) has shown neuroprotective and antioxidant effects in some neurodegenerative diseases. In this work, we de...

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Detalles Bibliográficos
Autores principales: Martín-Montañez, Elisa, Valverde, Nadia, Ladrón de Guevara-Miranda, David, Lara, Estrella, Romero-Zerbo, Yanina S., Millon, Carmelo, Boraldi, Federica, Ávila-Gámiz, Fabiola, Pérez-Cano, Ana M., Garrido-Gil, Pablo, Labandeira-Garcia, Jose Luis, Santin, Luis J., Pavia, Jose, Garcia-Fernandez, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379511/
https://www.ncbi.nlm.nih.gov/pubmed/34418603
http://dx.doi.org/10.1016/j.redox.2021.102095