Cargando…

Functional analysis of a monoclonal antibody reactive against the C1C2 of Env obtained from a patient infected with HIV-1 CRF02_AG

BACKGROUND: Recent data suggest the importance of non-neutralizing antibodies (nnAbs) in the development of vaccines against HIV-1 because two types of nnAbs that recognize the coreceptor binding site (CoRBS) and the C1C2 region mediate antibody-dependent cellular-cytotoxicity (ADCC) against HIV-1-i...

Descripción completa

Detalles Bibliográficos
Autores principales: Md Zahid, Hasan, Kuwata, Takeo, Takahama, Shokichi, Kaku, Yu, Biswas, Shashwata, Matsumoto, Kaho, Tamamura, Hirokazu, Matsushita, Shuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379604/
https://www.ncbi.nlm.nih.gov/pubmed/34419098
http://dx.doi.org/10.1186/s12977-021-00568-y