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Mahalanobis distance, a novel statistical proxy of homeostasis loss is longitudinally associated with risk of type 2 diabetes

BACKGROUND: The potential role of individual plasma biomarkers in the pathogenesis of type 2 diabetes (T2D) has been broadly studied, but the impact of biomarkers interaction remains underexplored. Recently, the Mahalanobis distance (MD) of plasma biomarkers has been proposed as a proxy of physiolog...

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Detalles Bibliográficos
Autores principales: Flores-Guerrero, Jose L., Grzegorczyk, Marco A., Connelly, Margery A., Garcia, Erwin, Navis, Gerjan, Dullaart, Robin P.F., Bakker, Stephan J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379628/
https://www.ncbi.nlm.nih.gov/pubmed/34425309
http://dx.doi.org/10.1016/j.ebiom.2021.103550