Neuroprotective derivatives of tacrine that target NMDA receptor and acetyl cholinesterase – Design, synthesis and biological evaluation

The complex and multifactorial nature of neuropsychiatric diseases demands multi-target drugs that can intervene with various sub-pathologies underlying disease progression. Targeting the impairments in cholinergic and glutamatergic neurotransmissions with small molecules has been suggested as one o...

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Detalles Bibliográficos
Autores principales: Remya, Chandran, Dileep, K.V., Koti Reddy, Eeda, Mantosh, Kumar, Lakshmi, Kesavan, Sarah Jacob, Reena, Sajith, Ayyiliyath M., Jayadevi Variyar, E., Anwar, Shaik, Zhang, Kam Y.J., Sadasivan, C., Omkumar, R.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379669/
https://www.ncbi.nlm.nih.gov/pubmed/34471497
http://dx.doi.org/10.1016/j.csbj.2021.07.041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379669/
https://www.ncbi.nlm.nih.gov/pubmed/34471497
http://dx.doi.org/10.1016/j.csbj.2021.07.041

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