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TREK channel activation suppresses migraine pain phenotype

Activation and sensitization of trigeminal ganglia (TG) sensory neurons, leading to the release of pro-inflammatory peptides such as calcitonin gene-related peptide (CGRP), are likely a key component in migraine-related headache induction. Reducing TG neuron excitability represents therefore an attr...

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Detalles Bibliográficos
Autores principales: Ávalos Prado, Pablo, Landra-Willm, Arnaud, Verkest, Clément, Ribera, Aurore, Chassot, Anne-Amandine, Baron, Anne, Sandoz, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379698/
https://www.ncbi.nlm.nih.gov/pubmed/34458705
http://dx.doi.org/10.1016/j.isci.2021.102961