RGD Peptide and PAD4 Inhibitor-Loaded Gold Nanorods for Chemo-Photothermal Combined Therapy to Inhibit Tumor Growth, Prevent Lung Metastasis and Improve Biosafety

PURPOSE: A targeted drug delivery system that combines protein-arginine deiminase type-4 (PAD4) inhibitors YW3-56 (356) with PTT of NPs is constructed to both decrease the accumulation of gold in metabolic organs and reduce the dose of chemotherapeutic agents. PATIENTS AND METHODS: In vitro cytotoxi...

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Detalles Bibliográficos
Autores principales: Lu, Yu, Peng, Zidong, Zhu, Di, Jia, Yijiang, Taledaohan, Ayijiang, Li, Yuanming, Liu, Jiawang, Wang, Yanming, Wang, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379711/
https://www.ncbi.nlm.nih.gov/pubmed/34429600
http://dx.doi.org/10.2147/IJN.S319210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379711/
https://www.ncbi.nlm.nih.gov/pubmed/34429600
http://dx.doi.org/10.2147/IJN.S319210

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