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RGD Peptide and PAD4 Inhibitor-Loaded Gold Nanorods for Chemo-Photothermal Combined Therapy to Inhibit Tumor Growth, Prevent Lung Metastasis and Improve Biosafety
PURPOSE: A targeted drug delivery system that combines protein-arginine deiminase type-4 (PAD4) inhibitors YW3-56 (356) with PTT of NPs is constructed to both decrease the accumulation of gold in metabolic organs and reduce the dose of chemotherapeutic agents. PATIENTS AND METHODS: In vitro cytotoxi...
Autores principales: | Lu, Yu, Peng, Zidong, Zhu, Di, Jia, Yijiang, Taledaohan, Ayijiang, Li, Yuanming, Liu, Jiawang, Wang, Yanming, Wang, Yuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379711/ https://www.ncbi.nlm.nih.gov/pubmed/34429600 http://dx.doi.org/10.2147/IJN.S319210 |
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