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Tetraspanins are unevenly distributed across single extracellular vesicles and bias sensitivity to multiplexed cancer biomarkers

BACKGROUND: Tetraspanin expression of extracellular vesicles (EVs) is often used as a surrogate for their detection and classification, a practice that typically assumes their consistent expression across EV sources. RESULTS: Here we demonstrate that there are distinct patterns in colocalization of...

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Detalles Bibliográficos
Autores principales: Mizenko, Rachel R., Brostoff, Terza, Rojalin, Tatu, Koster, Hanna J., Swindell, Hila S., Leiserowitz, Gary S., Wang, Aijun, Carney, Randy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379740/
https://www.ncbi.nlm.nih.gov/pubmed/34419056
http://dx.doi.org/10.1186/s12951-021-00987-1