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RIPK3 activation induces TRIM28 derepression in cancer cells and enhances the anti-tumor microenvironment

BACKGROUND: Necroptosis is emerging as a new target for cancer immunotherapy as it is now recognized as a form of cell death that increases tumor immunogenicity, which would be especially helpful in treating immune-desert tumors. De novo synthesis of inflammatory proteins during necroptosis appears...

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Detalles Bibliográficos
Autores principales: Park, Han-Hee, Kim, Hwa-Ryeon, Park, Sang-Yeong, Hwang, Sung-Min, Hong, Sun Mi, Park, Sangwook, Kang, Ho Chul, Morgan, Michael J., Cha, Jong-Ho, Lee, Dakeun, Roe, Jae-Seok, Kim, You-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379748/
https://www.ncbi.nlm.nih.gov/pubmed/34419074
http://dx.doi.org/10.1186/s12943-021-01399-3