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RIPK3 activation induces TRIM28 derepression in cancer cells and enhances the anti-tumor microenvironment
BACKGROUND: Necroptosis is emerging as a new target for cancer immunotherapy as it is now recognized as a form of cell death that increases tumor immunogenicity, which would be especially helpful in treating immune-desert tumors. De novo synthesis of inflammatory proteins during necroptosis appears...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379748/ https://www.ncbi.nlm.nih.gov/pubmed/34419074 http://dx.doi.org/10.1186/s12943-021-01399-3 |