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RVG-functionalized reduction sensitive micelles for the effective accumulation of doxorubicin in brain
BACKGROUND: Glioblastoma is a lethal neoplasm with few effective therapy options. As a mainstay in the current treatment of glioma at present, chemotherapeutic agents usually show inadequate therapeutic efficiency due to their low blood brain barrier traversal and brain targeting, together with tumo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379803/ https://www.ncbi.nlm.nih.gov/pubmed/34419071 http://dx.doi.org/10.1186/s12951-021-00997-z |