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RVG-functionalized reduction sensitive micelles for the effective accumulation of doxorubicin in brain

BACKGROUND: Glioblastoma is a lethal neoplasm with few effective therapy options. As a mainstay in the current treatment of glioma at present, chemotherapeutic agents usually show inadequate therapeutic efficiency due to their low blood brain barrier traversal and brain targeting, together with tumo...

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Detalles Bibliográficos
Autores principales: Xu, Jiangkang, Yang, Xiaoye, Ji, Jianbo, Gao, Yuan, Qiu, Na, Xi, Yanwei, Liu, Anchang, Zhai, Guangxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379803/
https://www.ncbi.nlm.nih.gov/pubmed/34419071
http://dx.doi.org/10.1186/s12951-021-00997-z