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DNA methylome profiling reveals epigenetic regulation of lipoprotein-associated phospholipase A(2) in human vulnerable atherosclerotic plaque

BACKGROUND: Atherosclerotic plaque vulnerability is a key feature of atheroprogression and precipitating acute cardiovascular events. Although the pivotal role of epigenetic regulation in atherosclerotic plaque destabilization is being recognized, the DNA methylation profile and its potential role i...

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Detalles Bibliográficos
Autores principales: Li, Jingjin, Zhang, Xiaoping, Yang, Mengxi, Yang, Hang, Xu, Ning, Fan, Xueqiang, Liu, Gang, Jiang, Xintong, Fan, Jiasai, Zhang, Lifang, Zhang, Hu, Zhou, Ying, Li, Rui, Gao, Si, Jin, Jiangli, Jin, Zening, Zheng, Jingang, Tu, Qiang, Ren, Jingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379831/
https://www.ncbi.nlm.nih.gov/pubmed/34419168
http://dx.doi.org/10.1186/s13148-021-01152-z