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Increased plasmin-mediated proteolysis of L1CAM in a mouse model of idiopathic normal pressure hydrocephalus

Idiopathic normal pressure hydrocephalus (iNPH) is a common neurological disorder that is characterized by enlarged cerebral ventricles, gait difficulty, incontinence, and dementia. iNPH usually develops after the sixth decade of life in previously asymptomatic individuals. We recently reported that...

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Detalles Bibliográficos
Autores principales: Yang, Dejun, Yang, Hongwei, Luiselli, Gabrielle, Ogagan, Charles, Dai, Huijun, Chiu, Lucinda, Carroll, Rona S., Johnson, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379912/
https://www.ncbi.nlm.nih.gov/pubmed/34380733
http://dx.doi.org/10.1073/pnas.2010528118