Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Na(v)1.5

The voltage-gated sodium channel Na(v)1.5 initiates the cardiac action potential. Alterations of its activation and inactivation properties due to mutations can cause severe, life-threatening arrhythmias. Yet despite intensive research efforts, many functional aspects of this cardiac channel remain...

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Detalles Bibliográficos
Autores principales: Galleano, Iacopo, Harms, Hendrik, Choudhury, Koushik, Khoo, Keith, Delemotte, Lucie, Pless, Stephan Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379932/
https://www.ncbi.nlm.nih.gov/pubmed/34373326
http://dx.doi.org/10.1073/pnas.2025320118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379932/
https://www.ncbi.nlm.nih.gov/pubmed/34373326
http://dx.doi.org/10.1073/pnas.2025320118

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