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Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Na(v)1.5
The voltage-gated sodium channel Na(v)1.5 initiates the cardiac action potential. Alterations of its activation and inactivation properties due to mutations can cause severe, life-threatening arrhythmias. Yet despite intensive research efforts, many functional aspects of this cardiac channel remain...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379932/ https://www.ncbi.nlm.nih.gov/pubmed/34373326 http://dx.doi.org/10.1073/pnas.2025320118 |