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HMGB1 released from nociceptors mediates inflammation

Inflammation, the body’s primary defensive response system to injury and infection, is triggered by molecular signatures of microbes and tissue injury. These molecules also stimulate specialized sensory neurons, termed nociceptors. Activation of nociceptors mediates inflammation through antidromic r...

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Detalles Bibliográficos
Autores principales: Yang, Huan, Zeng, Qiong, Silverman, Harold A., Gunasekaran, Manojkumar, George, Sam J., Devarajan, Alex, Addorisio, Meghan E., Li, Jianhua, Tsaava, Téa, Shah, Vivek, Billiar, Timothy R., Wang, Haichao, Brines, Michael, Andersson, Ulf, Pavlov, Valentin A., Chang, Eric H., Chavan, Sangeeta S., Tracey, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379951/
https://www.ncbi.nlm.nih.gov/pubmed/34385304
http://dx.doi.org/10.1073/pnas.2102034118