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Modulation of mitochondrial nucleoid structure during aging and by mtDNA content in Drosophila

Mitochondrial DNA (mtDNA) encodes gene products that are essential for oxidative phosphorylation. They organize as higher order nucleoid structures (mtNucleoids) that were shown to be critical for the maintenance of mtDNA stability and integrity. While mtNucleoid structures are associated with cellu...

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Detalles Bibliográficos
Autores principales: Wang, Li-jie, Hsu, Tian, Lin, Hsiang-ling, Fu, Chi-yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380045/
https://www.ncbi.nlm.nih.gov/pubmed/34180963
http://dx.doi.org/10.1242/bio.058553