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Mitoquinone Protects Podocytes from Angiotensin II-Induced Mitochondrial Dysfunction and Injury via the Keap1-Nrf2 Signaling Pathway

Podocyte mitochondrial dysfunction plays a critical role in the pathogenesis of chronic kidney disease (CKD). Previous studies demonstrated that excessive mitochondrial fission could lead to the overproduction of reactive oxygen species (ROS) and promote podocyte apoptosis. Therefore, the maintenanc...

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Detalles Bibliográficos
Autores principales: Zhu, Zijing, Liang, Wei, Chen, Zhaowei, Hu, Jijia, Feng, Jun, Cao, Yun, Ma, Yiqiong, Ding, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380182/
https://www.ncbi.nlm.nih.gov/pubmed/34426758
http://dx.doi.org/10.1155/2021/1394486